The PAIN Special Interest Group (PAIN SIG) is comprised of investigators from a number of different institutes and centers at the NIH that are interested in the neurobiological mechanisms underlying pain. Our group is moderated by Drs. Yarimar Carrasquillo, Alex Chesler, and Lauren Chesler and includes students, postdocs, postbacs, staff, investigators, and clinicians. Research areas of interest span from molecular and cellular studies in model systems to clinical studies in both healthy individuals and pain patients. Our goal is to provide a forum where researchers from different backgrounds can openly exchange their ideas and perspectives as well as discuss the latest technical approaches for the study of pain.